{
  "resourceType": "CodeSystem",
  "id": "certainty-type",
  "meta": {
    "profile": [
      "http://hl7.org/fhir/StructureDefinition/shareablecodesystem"
    ]
  },
  "language": "en",
  "text": {
    "status": "generated",
    "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\" xml:lang=\"en\" lang=\"en\"><p class=\"res-header-id\"><b>Generated Narrative: CodeSystem certainty-type</b></p><a name=\"certainty-type\"> </a><a name=\"hccertainty-type\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Language: en</p><p style=\"margin-bottom: 0px\">Profile: <a href=\"http://hl7.org/fhir/R5/shareablecodesystem.html\">Shareable CodeSystem</a></p></div><p>This case-sensitive code system <code>http://terminology.hl7.org/CodeSystem/certainty-type</code> defines the following codes:</p><table class=\"codes\"><tr><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td><td><b>Definition</b></td></tr><tr><td style=\"white-space:nowrap\">Overall<a name=\"certainty-type-Overall\"> </a></td><td>Overall certainty</td><td>Overall certainty of evidence (quality of evidence).</td></tr><tr><td style=\"white-space:nowrap\">RiskOfBias<a name=\"certainty-type-RiskOfBias\"> </a></td><td>Risk of bias</td><td>methodologic concerns reducing internal validity.</td></tr><tr><td style=\"white-space:nowrap\">Inconsistency<a name=\"certainty-type-Inconsistency\"> </a></td><td>Inconsistency</td><td>concerns that findings are not similar enough to support certainty.</td></tr><tr><td style=\"white-space:nowrap\">Indirectness<a name=\"certainty-type-Indirectness\"> </a></td><td>Indirectness</td><td>concerns reducing external validity.</td></tr><tr><td style=\"white-space:nowrap\">Imprecision<a name=\"certainty-type-Imprecision\"> </a></td><td>Imprecision</td><td>fuzzy or wide variability.</td></tr><tr><td style=\"white-space:nowrap\">PublicationBias<a name=\"certainty-type-PublicationBias\"> </a></td><td>Publication bias</td><td>likelihood that what is published misrepresents what is available to publish.</td></tr><tr><td style=\"white-space:nowrap\">DoseResponseGradient<a name=\"certainty-type-DoseResponseGradient\"> </a></td><td>Dose response gradient</td><td>higher certainty due to dose response relationship.</td></tr><tr><td style=\"white-space:nowrap\">PlausibleConfounding<a name=\"certainty-type-PlausibleConfounding\"> </a></td><td>Plausible confounding</td><td>higher certainty due to risk of bias in opposite direction.</td></tr><tr><td style=\"white-space:nowrap\">LargeEffect<a name=\"certainty-type-LargeEffect\"> </a></td><td>Large effect</td><td>higher certainty due to large effect size.</td></tr></table></div>"
  },
  "extension": [
    {
      "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg",
      "valueCode": "cds"
    },
    {
      "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
      "valueCode": "trial-use"
    },
    {
      "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm",
      "valueInteger": 1
    }
  ],
  "url": "http://terminology.hl7.org/CodeSystem/certainty-type",
  "version": "1.0.0",
  "name": "EvidenceCertaintyType",
  "title": "Evidence Certainty Type",
  "status": "active",
  "experimental": false,
  "date": "2025-01-20T16:55:11+11:00",
  "publisher": "HL7 (FHIR Project)",
  "contact": [
    {
      "telecom": [
        {
          "system": "url",
          "value": "http://hl7.org/fhir"
        },
        {
          "system": "email",
          "value": "fhir@lists.hl7.org"
        }
      ]
    }
  ],
  "description": "The aspect of quality, confidence, or certainty.",
  "caseSensitive": true,
  "valueSet": "http://terminology.hl7.org/ValueSet/certainty-type",
  "content": "complete",
  "concept": [
    {
      "code": "Overall",
      "display": "Overall certainty",
      "definition": "Overall certainty of evidence (quality of evidence)."
    },
    {
      "code": "RiskOfBias",
      "display": "Risk of bias",
      "definition": "methodologic concerns reducing internal validity."
    },
    {
      "code": "Inconsistency",
      "display": "Inconsistency",
      "definition": "concerns that findings are not similar enough to support certainty."
    },
    {
      "code": "Indirectness",
      "display": "Indirectness",
      "definition": "concerns reducing external validity."
    },
    {
      "code": "Imprecision",
      "display": "Imprecision",
      "definition": "fuzzy or wide variability."
    },
    {
      "code": "PublicationBias",
      "display": "Publication bias",
      "definition": "likelihood that what is published misrepresents what is available to publish."
    },
    {
      "code": "DoseResponseGradient",
      "display": "Dose response gradient",
      "definition": "higher certainty due to dose response relationship."
    },
    {
      "code": "PlausibleConfounding",
      "display": "Plausible confounding",
      "definition": "higher certainty due to risk of bias in opposite direction."
    },
    {
      "code": "LargeEffect",
      "display": "Large effect",
      "definition": "higher certainty due to large effect size."
    }
  ]
}