<?xml version="1.0" encoding="UTF-8"?>
<CodeSystem xmlns="http://hl7.org/fhir">
  <id value="evidence-classifier-code"/>
  <meta>
    <lastUpdated value="2023-03-26T15:21:02.749+11:00"/>
    <profile value="http://hl7.org/fhir/StructureDefinition/shareablecodesystem"/>
  </meta>
  <text>
    <status value="generated"/>
    <div value="&lt;div xmlns=&quot;http://www.w3.org/1999/xhtml&quot;&gt;
            &lt;p&gt;This code system 
              &lt;code&gt;http://hl7.org/fhir/evidence-classifier-code&lt;/code&gt; defines the following codes:
            &lt;/p&gt;
            &lt;table class=&quot;codes&quot;&gt;
              &lt;tr&gt;
                &lt;td style=&quot;white-space:nowrap&quot;&gt;
                  &lt;b&gt;Code&lt;/b&gt;
                &lt;/td&gt;
                &lt;td&gt;
                  &lt;b&gt;Display&lt;/b&gt;
                &lt;/td&gt;
                &lt;td&gt;
                  &lt;b&gt;Definition&lt;/b&gt;
                &lt;/td&gt;
              &lt;/tr&gt;
              &lt;tr&gt;
                &lt;td style=&quot;white-space:nowrap&quot;&gt;COVID19Specific
                  &lt;a name=&quot;evidence-classifier-code-COVID19Specific&quot;&gt; &lt;/a&gt;
                &lt;/td&gt;
                &lt;td&gt;COVID-19 specific article&lt;/td&gt;
                &lt;td&gt;About COVID-19.&lt;/td&gt;
              &lt;/tr&gt;
              &lt;tr&gt;
                &lt;td style=&quot;white-space:nowrap&quot;&gt;COVID19Relevant
                  &lt;a name=&quot;evidence-classifier-code-COVID19Relevant&quot;&gt; &lt;/a&gt;
                &lt;/td&gt;
                &lt;td&gt;COVID-19 relevant (but not specific) article&lt;/td&gt;
                &lt;td&gt;Not about COVID-19 but relevant to COVID-19 management or understanding.&lt;/td&gt;
              &lt;/tr&gt;
              &lt;tr&gt;
                &lt;td style=&quot;white-space:nowrap&quot;&gt;COVID19HumanResearch
                  &lt;a name=&quot;evidence-classifier-code-COVID19HumanResearch&quot;&gt; &lt;/a&gt;
                &lt;/td&gt;
                &lt;td&gt;COVID-19 human data in population, exposure, or outcome&lt;/td&gt;
                &lt;td&gt;contains human COVID-19 disease in the research data as any variable (population, exposure or outcome).&lt;/td&gt;
              &lt;/tr&gt;
              &lt;tr&gt;
                &lt;td style=&quot;white-space:nowrap&quot;&gt;OriginalResearch
                  &lt;a name=&quot;evidence-classifier-code-OriginalResearch&quot;&gt; &lt;/a&gt;
                &lt;/td&gt;
                &lt;td&gt;Article includes original research&lt;/td&gt;
                &lt;td&gt;such as randomized trial, observational study.&lt;/td&gt;
              &lt;/tr&gt;
              &lt;tr&gt;
                &lt;td style=&quot;white-space:nowrap&quot;&gt;ResearchSynthesis
                  &lt;a name=&quot;evidence-classifier-code-ResearchSynthesis&quot;&gt; &lt;/a&gt;
                &lt;/td&gt;
                &lt;td&gt;Article includes synthesis of research&lt;/td&gt;
                &lt;td&gt;such as systematic review, meta-analysis, rapid review.&lt;/td&gt;
              &lt;/tr&gt;
              &lt;tr&gt;
                &lt;td style=&quot;white-space:nowrap&quot;&gt;Guideline
                  &lt;a name=&quot;evidence-classifier-code-Guideline&quot;&gt; &lt;/a&gt;
                &lt;/td&gt;
                &lt;td&gt;Article includes guideline&lt;/td&gt;
                &lt;td&gt;for clinical practice guidelines.&lt;/td&gt;
              &lt;/tr&gt;
              &lt;tr&gt;
                &lt;td style=&quot;white-space:nowrap&quot;&gt;ResearchProtocol
                  &lt;a name=&quot;evidence-classifier-code-ResearchProtocol&quot;&gt; &lt;/a&gt;
                &lt;/td&gt;
                &lt;td&gt;Article provides protocol without results&lt;/td&gt;
                &lt;td&gt;for research protocols.&lt;/td&gt;
              &lt;/tr&gt;
              &lt;tr&gt;
                &lt;td style=&quot;white-space:nowrap&quot;&gt;NotResearchNotGuideline
                  &lt;a name=&quot;evidence-classifier-code-NotResearchNotGuideline&quot;&gt; &lt;/a&gt;
                &lt;/td&gt;
                &lt;td&gt;Article is neither research nor guideline&lt;/td&gt;
                &lt;td&gt;for things that are not research reports, research protocols or guidelines.&lt;/td&gt;
              &lt;/tr&gt;
              &lt;tr&gt;
                &lt;td style=&quot;white-space:nowrap&quot;&gt;Treatment
                  &lt;a name=&quot;evidence-classifier-code-Treatment&quot;&gt; &lt;/a&gt;
                &lt;/td&gt;
                &lt;td&gt;Article about treatment&lt;/td&gt;
                &lt;td&gt;about therapeutic interventions.&lt;/td&gt;
              &lt;/tr&gt;
              &lt;tr&gt;
                &lt;td style=&quot;white-space:nowrap&quot;&gt;PreventionAndControl
                  &lt;a name=&quot;evidence-classifier-code-PreventionAndControl&quot;&gt; &lt;/a&gt;
                &lt;/td&gt;
                &lt;td&gt;Article about prevention and control&lt;/td&gt;
                &lt;td&gt;about preventive care and interventions.&lt;/td&gt;
              &lt;/tr&gt;
              &lt;tr&gt;
                &lt;td style=&quot;white-space:nowrap&quot;&gt;Diagnosis
                  &lt;a name=&quot;evidence-classifier-code-Diagnosis&quot;&gt; &lt;/a&gt;
                &lt;/td&gt;
                &lt;td&gt;Article about diagnosis&lt;/td&gt;
                &lt;td&gt;about methods to distinguish having or not having a condition.&lt;/td&gt;
              &lt;/tr&gt;
              &lt;tr&gt;
                &lt;td style=&quot;white-space:nowrap&quot;&gt;PrognosisPrediction
                  &lt;a name=&quot;evidence-classifier-code-PrognosisPrediction&quot;&gt; &lt;/a&gt;
                &lt;/td&gt;
                &lt;td&gt;Article about prognosis or prediction&lt;/td&gt;
                &lt;td&gt;about predicting risk for something or risk factors for it.&lt;/td&gt;
              &lt;/tr&gt;
              &lt;tr&gt;
                &lt;td style=&quot;white-space:nowrap&quot;&gt;RatedAsYes
                  &lt;a name=&quot;evidence-classifier-code-RatedAsYes&quot;&gt; &lt;/a&gt;
                &lt;/td&gt;
                &lt;td&gt;Rated as yes, affirmative, positive, present, or include&lt;/td&gt;
                &lt;td/&gt;
              &lt;/tr&gt;
              &lt;tr&gt;
                &lt;td style=&quot;white-space:nowrap&quot;&gt;RatedAsNo
                  &lt;a name=&quot;evidence-classifier-code-RatedAsNo&quot;&gt; &lt;/a&gt;
                &lt;/td&gt;
                &lt;td&gt;Rated as no, negative, absent, or exclude&lt;/td&gt;
                &lt;td&gt;Rated as no, negative, absent, or exclude.&lt;/td&gt;
              &lt;/tr&gt;
              &lt;tr&gt;
                &lt;td style=&quot;white-space:nowrap&quot;&gt;NotAssessed
                  &lt;a name=&quot;evidence-classifier-code-NotAssessed&quot;&gt; &lt;/a&gt;
                &lt;/td&gt;
                &lt;td&gt;Not rated, not assessed&lt;/td&gt;
                &lt;td&gt;Neither rated as yes nor rated as no.&lt;/td&gt;
              &lt;/tr&gt;
              &lt;tr&gt;
                &lt;td style=&quot;white-space:nowrap&quot;&gt;RatedAsRCT
                  &lt;a name=&quot;evidence-classifier-code-RatedAsRCT&quot;&gt; &lt;/a&gt;
                &lt;/td&gt;
                &lt;td&gt;classified as randomized controlled trial&lt;/td&gt;
                &lt;td&gt;classified as randomized controlled trial.&lt;/td&gt;
              &lt;/tr&gt;
              &lt;tr&gt;
                &lt;td style=&quot;white-space:nowrap&quot;&gt;RatedAsControlledTrial
                  &lt;a name=&quot;evidence-classifier-code-RatedAsControlledTrial&quot;&gt; &lt;/a&gt;
                &lt;/td&gt;
                &lt;td&gt;classified as nonrandomized controlled trial (experimental)&lt;/td&gt;
                &lt;td&gt;classified as nonrandomized controlled trial (experimental).&lt;/td&gt;
              &lt;/tr&gt;
              &lt;tr&gt;
                &lt;td style=&quot;white-space:nowrap&quot;&gt;RatedAsComparativeCohort
                  &lt;a name=&quot;evidence-classifier-code-RatedAsComparativeCohort&quot;&gt; &lt;/a&gt;
                &lt;/td&gt;
                &lt;td&gt;classified as comparative cohort study (observational)&lt;/td&gt;
                &lt;td&gt;classified as comparative cohort study (observational).&lt;/td&gt;
              &lt;/tr&gt;
              &lt;tr&gt;
                &lt;td style=&quot;white-space:nowrap&quot;&gt;RatedAsCaseControl
                  &lt;a name=&quot;evidence-classifier-code-RatedAsCaseControl&quot;&gt; &lt;/a&gt;
                &lt;/td&gt;
                &lt;td&gt;classified as case-control study&lt;/td&gt;
                &lt;td&gt;classified as case-control study.&lt;/td&gt;
              &lt;/tr&gt;
              &lt;tr&gt;
                &lt;td style=&quot;white-space:nowrap&quot;&gt;RatedAsUncontrolledSeries
                  &lt;a name=&quot;evidence-classifier-code-RatedAsUncontrolledSeries&quot;&gt; &lt;/a&gt;
                &lt;/td&gt;
                &lt;td&gt;classified as uncontrolled cohort (case series)&lt;/td&gt;
                &lt;td&gt;classified as uncontrolled cohort (case series).&lt;/td&gt;
              &lt;/tr&gt;
              &lt;tr&gt;
                &lt;td style=&quot;white-space:nowrap&quot;&gt;RatedAsMixedMethods
                  &lt;a name=&quot;evidence-classifier-code-RatedAsMixedMethods&quot;&gt; &lt;/a&gt;
                &lt;/td&gt;
                &lt;td&gt;classified as mixed-methods study&lt;/td&gt;
                &lt;td&gt;classified as mixed-methods study.&lt;/td&gt;
              &lt;/tr&gt;
              &lt;tr&gt;
                &lt;td style=&quot;white-space:nowrap&quot;&gt;RatedAsOther
                  &lt;a name=&quot;evidence-classifier-code-RatedAsOther&quot;&gt; &lt;/a&gt;
                &lt;/td&gt;
                &lt;td&gt;classified as other concept (not elsewhere classified)&lt;/td&gt;
                &lt;td&gt;classified as other concept (not elsewhere classified).&lt;/td&gt;
              &lt;/tr&gt;
              &lt;tr&gt;
                &lt;td style=&quot;white-space:nowrap&quot;&gt;RiskOfBias
                  &lt;a name=&quot;evidence-classifier-code-RiskOfBias&quot;&gt; &lt;/a&gt;
                &lt;/td&gt;
                &lt;td&gt;Risk of bias assessment&lt;/td&gt;
                &lt;td&gt;Risk of bias assessment.&lt;/td&gt;
              &lt;/tr&gt;
              &lt;tr&gt;
                &lt;td style=&quot;white-space:nowrap&quot;&gt;NoBlinding
                  &lt;a name=&quot;evidence-classifier-code-NoBlinding&quot;&gt; &lt;/a&gt;
                &lt;/td&gt;
                &lt;td&gt;No blinding&lt;/td&gt;
                &lt;td&gt;No blinding.&lt;/td&gt;
              &lt;/tr&gt;
              &lt;tr&gt;
                &lt;td style=&quot;white-space:nowrap&quot;&gt;AllocConcealNotStated
                  &lt;a name=&quot;evidence-classifier-code-AllocConcealNotStated&quot;&gt; &lt;/a&gt;
                &lt;/td&gt;
                &lt;td&gt;Allocation concealment not stated&lt;/td&gt;
                &lt;td&gt;Allocation concealment not stated.&lt;/td&gt;
              &lt;/tr&gt;
              &lt;tr&gt;
                &lt;td style=&quot;white-space:nowrap&quot;&gt;EarlyTrialTermination
                  &lt;a name=&quot;evidence-classifier-code-EarlyTrialTermination&quot;&gt; &lt;/a&gt;
                &lt;/td&gt;
                &lt;td&gt;Early trial termination&lt;/td&gt;
                &lt;td&gt;Early trial termination.&lt;/td&gt;
              &lt;/tr&gt;
              &lt;tr&gt;
                &lt;td style=&quot;white-space:nowrap&quot;&gt;NoITT
                  &lt;a name=&quot;evidence-classifier-code-NoITT&quot;&gt; &lt;/a&gt;
                &lt;/td&gt;
                &lt;td&gt;No intention-to-treat analysis&lt;/td&gt;
                &lt;td&gt;No intention-to-treat analysis.&lt;/td&gt;
              &lt;/tr&gt;
              &lt;tr&gt;
                &lt;td style=&quot;white-space:nowrap&quot;&gt;Preprint
                  &lt;a name=&quot;evidence-classifier-code-Preprint&quot;&gt; &lt;/a&gt;
                &lt;/td&gt;
                &lt;td&gt;Preprint (not final publication)&lt;/td&gt;
                &lt;td&gt;Results presented in preprint (pre-final publication) form.&lt;/td&gt;
              &lt;/tr&gt;
              &lt;tr&gt;
                &lt;td style=&quot;white-space:nowrap&quot;&gt;PreliminaryAnalysis
                  &lt;a name=&quot;evidence-classifier-code-PreliminaryAnalysis&quot;&gt; &lt;/a&gt;
                &lt;/td&gt;
                &lt;td&gt;Preliminary analysis&lt;/td&gt;
                &lt;td&gt;Preliminary analysis.&lt;/td&gt;
              &lt;/tr&gt;
              &lt;tr&gt;
                &lt;td style=&quot;white-space:nowrap&quot;&gt;BaselineImbalance
                  &lt;a name=&quot;evidence-classifier-code-BaselineImbalance&quot;&gt; &lt;/a&gt;
                &lt;/td&gt;
                &lt;td&gt;Baseline imbalances&lt;/td&gt;
                &lt;td&gt;Differences between groups at start of trial may confound or bias the findings.&lt;/td&gt;
              &lt;/tr&gt;
              &lt;tr&gt;
                &lt;td style=&quot;white-space:nowrap&quot;&gt;SubgroupAnalysis
                  &lt;a name=&quot;evidence-classifier-code-SubgroupAnalysis&quot;&gt; &lt;/a&gt;
                &lt;/td&gt;
                &lt;td&gt;Subgroup analysis&lt;/td&gt;
                &lt;td&gt;Subgroup analysis.&lt;/td&gt;
              &lt;/tr&gt;
            &lt;/table&gt;
          &lt;/div&gt;"/>
  </text>
  <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-wg">
    <valueCode value="cds"/>
  </extension>
  <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status">
    <valueCode value="trial-use"/>
  </extension>
  <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm">
    <valueInteger value="0"/>
  </extension>
  <url value="http://hl7.org/fhir/evidence-classifier-code"/>
  <identifier>
    <system value="urn:ietf:rfc:3986"/>
    <value value="urn:oid:2.16.840.1.113883.4.642.4.1959"/>
  </identifier>
  <version value="5.0.0"/>
  <name value="EvidenceClassifier"/>
  <title value="Evidence Classifier"/>
  <status value="active"/>
  <experimental value="false"/>
  <date value="2020-12-28T16:55:11+11:00"/>
  <publisher value="HL7 (FHIR Project)"/>
  <contact>
    <telecom>
      <system value="url"/>
      <value value="http://hl7.org/fhir"/>
    </telecom>
    <telecom>
      <system value="email"/>
      <value value="fhir@lists.hl7.org"/>
    </telecom>
  </contact>
  <description value="Commonly used classifiers for evidence sets."/>
  <jurisdiction>
    <coding>
      <system value="http://unstats.un.org/unsd/methods/m49/m49.htm"/>
      <code value="001"/>
      <display value="World"/>
    </coding>
  </jurisdiction>
  <caseSensitive value="true"/>
  <valueSet value="http://hl7.org/fhir/ValueSet/evidence-classifier-code"/>
  <content value="complete"/>
  <concept>
    <code value="COVID19Specific"/>
    <display value="COVID-19 specific article"/>
    <definition value="About COVID-19."/>
  </concept>
  <concept>
    <code value="COVID19Relevant"/>
    <display value="COVID-19 relevant (but not specific) article"/>
    <definition value="Not about COVID-19 but relevant to COVID-19 management or understanding."/>
  </concept>
  <concept>
    <code value="COVID19HumanResearch"/>
    <display value="COVID-19 human data in population, exposure, or outcome"/>
    <definition value="contains human COVID-19 disease in the research data as any variable (population, exposure or outcome)."/>
  </concept>
  <concept>
    <code value="OriginalResearch"/>
    <display value="Article includes original research"/>
    <definition value="such as randomized trial, observational study."/>
  </concept>
  <concept>
    <code value="ResearchSynthesis"/>
    <display value="Article includes synthesis of research"/>
    <definition value="such as systematic review, meta-analysis, rapid review."/>
  </concept>
  <concept>
    <code value="Guideline"/>
    <display value="Article includes guideline"/>
    <definition value="for clinical practice guidelines."/>
  </concept>
  <concept>
    <code value="ResearchProtocol"/>
    <display value="Article provides protocol without results"/>
    <definition value="for research protocols."/>
  </concept>
  <concept>
    <code value="NotResearchNotGuideline"/>
    <display value="Article is neither research nor guideline"/>
    <definition value="for things that are not research reports, research protocols or guidelines."/>
  </concept>
  <concept>
    <code value="Treatment"/>
    <display value="Article about treatment"/>
    <definition value="about therapeutic interventions."/>
  </concept>
  <concept>
    <code value="PreventionAndControl"/>
    <display value="Article about prevention and control"/>
    <definition value="about preventive care and interventions."/>
  </concept>
  <concept>
    <code value="Diagnosis"/>
    <display value="Article about diagnosis"/>
    <definition value="about methods to distinguish having or not having a condition."/>
  </concept>
  <concept>
    <code value="PrognosisPrediction"/>
    <display value="Article about prognosis or prediction"/>
    <definition value="about predicting risk for something or risk factors for it."/>
  </concept>
  <concept>
    <code value="RatedAsYes"/>
    <display value="Rated as yes, affirmative, positive, present, or include"/>
  </concept>
  <concept>
    <code value="RatedAsNo"/>
    <display value="Rated as no, negative, absent, or exclude"/>
    <definition value="Rated as no, negative, absent, or exclude."/>
  </concept>
  <concept>
    <code value="NotAssessed"/>
    <display value="Not rated, not assessed"/>
    <definition value="Neither rated as yes nor rated as no."/>
  </concept>
  <concept>
    <code value="RatedAsRCT"/>
    <display value="classified as randomized controlled trial"/>
    <definition value="classified as randomized controlled trial."/>
  </concept>
  <concept>
    <code value="RatedAsControlledTrial"/>
    <display value="classified as nonrandomized controlled trial (experimental)"/>
    <definition value="classified as nonrandomized controlled trial (experimental)."/>
  </concept>
  <concept>
    <code value="RatedAsComparativeCohort"/>
    <display value="classified as comparative cohort study (observational)"/>
    <definition value="classified as comparative cohort study (observational)."/>
  </concept>
  <concept>
    <code value="RatedAsCaseControl"/>
    <display value="classified as case-control study"/>
    <definition value="classified as case-control study."/>
  </concept>
  <concept>
    <code value="RatedAsUncontrolledSeries"/>
    <display value="classified as uncontrolled cohort (case series)"/>
    <definition value="classified as uncontrolled cohort (case series)."/>
  </concept>
  <concept>
    <code value="RatedAsMixedMethods"/>
    <display value="classified as mixed-methods study"/>
    <definition value="classified as mixed-methods study."/>
  </concept>
  <concept>
    <code value="RatedAsOther"/>
    <display value="classified as other concept (not elsewhere classified)"/>
    <definition value="classified as other concept (not elsewhere classified)."/>
  </concept>
  <concept>
    <code value="RiskOfBias"/>
    <display value="Risk of bias assessment"/>
    <definition value="Risk of bias assessment."/>
  </concept>
  <concept>
    <code value="NoBlinding"/>
    <display value="No blinding"/>
    <definition value="No blinding."/>
  </concept>
  <concept>
    <code value="AllocConcealNotStated"/>
    <display value="Allocation concealment not stated"/>
    <definition value="Allocation concealment not stated."/>
  </concept>
  <concept>
    <code value="EarlyTrialTermination"/>
    <display value="Early trial termination"/>
    <definition value="Early trial termination."/>
  </concept>
  <concept>
    <code value="NoITT"/>
    <display value="No intention-to-treat analysis"/>
    <definition value="No intention-to-treat analysis."/>
  </concept>
  <concept>
    <code value="Preprint"/>
    <display value="Preprint (not final publication)"/>
    <definition value="Results presented in preprint (pre-final publication) form."/>
  </concept>
  <concept>
    <code value="PreliminaryAnalysis"/>
    <display value="Preliminary analysis"/>
    <definition value="Preliminary analysis."/>
  </concept>
  <concept>
    <code value="BaselineImbalance"/>
    <display value="Baseline imbalances"/>
    <definition value="Differences between groups at start of trial may confound or bias the findings."/>
  </concept>
  <concept>
    <code value="SubgroupAnalysis"/>
    <display value="Subgroup analysis"/>
    <definition value="Subgroup analysis."/>
  </concept>
</CodeSystem>