# description
 Identifies what sort of change is permitted or has occurred between the therapy that was ordered and the therapy that was/will be provided.

# property[].description
Indicates that the code is abstract - only intended to be used as a selector for other concepts

# concept[].definition
Description: Substitution occurred or is permitted with another product that may potentially have different ingredients, but having the same biological and therapeutic effects.

# concept[].concept[].definition
Description: Substitution occurred or is permitted with another bioequivalent and therapeutically equivalent product.

# concept[].concept[].concept[].definition
Description: 
                        

                        Substitution occurred or is permitted with another product that is a:

                        
                           pharmaceutical alternative containing the same active ingredient but is formulated with different salt, ester
                           pharmaceutical equivalent that has the same active ingredient, strength, dosage form and route of administration
                        
                        
                           Examples: 
                        

                        
                           
                              Pharmaceutical alternative: Erythromycin Ethylsuccinate for Erythromycin Stearate
                           
                              Pharmaceutical equivalent: Lisonpril for Zestril

# concept[].concept[].concept[].concept[].definition
Description: 
                        

                        Substitution occurred or is permitted between equivalent Brands but not Generics

                        
                           Examples: 
                        

                        
                           Zestril  for Prinivil
                           Coumadin for Jantoven

# concept[].concept[].concept[].concept[].definition
Description: Substitution occurred or is permitted between equivalent Generics but not Brands

                        
                           Examples: 
                        

                        
                           Lisnopril (Lupin Corp) for Lisnopril (Wockhardt Corp)

# concept[].concept[].concept[].definition
Description: Substitution occurred or is permitted with another product having the same therapeutic objective and safety profile.

                        
                           Examples: 
                        

                        
                           ranitidine for Tagamet

# concept[].concept[].concept[].concept[].definition
Description: Substitution occurred or is permitted between therapeutically equivalent Brands but not Generics
>
                           Examples: 
                        

                        
                           Zantac for Tagamet

# concept[].concept[].concept[].concept[].definition
Description: Substitution occurred or is permitted between therapeutically equivalent Generics but not Brands
>
                           Examples: 
                        

                        
                           Ranitidine  for cimetidine

# concept[].concept[].definition
Description: This substitution was performed or is permitted based on formulary guidelines.

# concept[].concept[].definition
No substitution occurred or is permitted.